By George A. Mansoor
This critical advisor significantly evaluates for high blood pressure experts either demonstrated and new thoughts for diagnosing and treating secondary high blood pressure in adults and kids. Drawing on quite a few clinical disciplines-including nephrology, endocrinology, inner drugs, and pediatrics-its world-renowned authors evaluate the severe situations that are supposed to urged a look for secondary sorts of high blood pressure, and element acceptable checking out for those unusual issues. extra insurance is given to exogenous or such less-appreciated factors of secondary high blood pressure as obstructive sleep apnea, fundamental aldosteronism, renovascular high blood pressure, and the results of noncardiac medications.
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Additional resources for Secondary Hypertension: Clinical Presentation, Diagnosis, and Treatment (Clinical Hypertension and Vascular Diseases)
Cushman WC, Cutler JA, Hanna E, et al. Prevention and treatment of hypertension study (PATHS): effects of an alcohol treatment program on blood pressure. Arch Intern Med 1998;158:1197–1207. 31. Brecklin CS, Gopaniuk-Folga A, Kravetz T, et al. Prevalence of hypertension in chronic cocaine users. Am J Hypertens 1998;11:1279–1283. 32. Taler SJ, Textor SC, Canzanello VJ, Schwartz L. Cyclosporin-induced hypertension: incidence, pathogenesis and management. Drug Saf 1999;20:437–449. 33. Blumenfeld JD, Laragh JH.
Circulation 1996;94: 483–489. 6. Bennet WM, Porter GA. Cyclosporine-associated hypertension. Am J Med 1988;85:131–133. 7. Levin N. Management of BP changes during recombinant human erythropoietin therapy. Semin Nephrol 1989;9(1 Suppl 2):16–20. 8. MacMahon S. Alcohol consumption and hypertension. Hypertension 1987;9: 111–121. 9. Pope JE, Anderson JJ, Felson DT. A meta-analysis of the effects of nonsteroidal anti-inflammatory drugs on blood pressure. Arch Intern Med 1993;153: 477–484. 10. Frishman WH.
The concomitant use of sympathomimetic agents and `-blockers can severely increase BP because of unopposed _-adrenergic vasoconstriction. The substitution of _-blockers or agents such as labetalol or carvedilol, which block both _- and `-adrenergic receptors, should prevent this detrimental reaction. Antiemetic agents such as metoclopramide, alizapride and prochlorperazine have been reported to increase BP transiently in patients treated with cisplatin. Yohimbine hydrochloride—an _2-adrenoceptor antagonist that is approved (but of questionable efficacy) for treatment of impotence— may significantly increase BP in hypertensive patients.
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